Osteoarthritis, often referred to as degenerative arthritis, is a non-inflammatory disease affecting predominately weight bearing joints like the knee and hip. It is not merely a disease of bone but represents a spectrum of degenerative disorders affecting one or more of the following joint components: bone, articular cartilage, meniscal cartilage, ligaments (the fibrous material that connects bone to bone), the joint capsule and synovial fluid, and, lastly, the pericapsular muscles and tendons. Continue reading
The Skeptical EP
The Blog Page of Robert Clare MDCredit: Non-Sequitur by Wiley Miller
“Questioning medical dogma to improve the lives of patients.”
Skepticism, from the Greek word skepticos (to inquire), is not simply a noun but a process. Skeptics demand evidence before accepting claims of truth; they enjoy the process of inquiry and analysis. Unlike cynics who take a negative view of both the claims of others and the people making them, skeptics are perfectly happy to change their minds when better evidence comes along. For physicians, a questioning attitude is an essential component to decision-making. When faced with increasing pressure from administrators and pharmaceutical companies to “Show me the money!” the best counter from the physician is “Show me the evidence!” The purpose of this blog is to raise awareness through an inquiry of the best available medical knowledge, to foster discussion, and to challenge prevailing truths in order to improve the lives of patients everywhere.
Disclaimer: The opinions put forth in this blog are just that: opinions. They should not be used as a substitute for your own good sense or that of your doctor. Readers of this column do so at their own risk—this blog is not intended to treat or diagnose disease. Information contained here should be considered a “dietary supplement.” None of it is FDA approved. Mistakes in data interpretation are mine alone (I don’t claim to be a statistician), and you should assume that mistakes will occasionally be made. All personal patient information has been altered.
In my last post I discussed prebiotics and probiotics. Now it’s on to antibiotics. At first glance it may seem odd that I am skeptical about a class of drugs that has saved countless lives, but it’s their effectiveness going forward and widespread misuse that concerns me. Unfortunately, when it comes to antibiotics these concerns are inextricably linked. Continue reading
The human body is a fierce and radiant jungle composed of more than 37 trillion cells. Muscle, bone, and brain; nephrons and neurons; hair and nails; rods and cones—it’s all in there. Such amazing diversity to support this enigmatic thing called Life. Continue reading
The US Preventative Services Task Force convened to re-examine the available data regarding screening mammography for breast cancer and released their recommendations this week. Continue reading
Flu season is upon us again with influenza now present in 48 states. So far, the disease has been only sporadically reported, although commercials for the anti-flu drug Tamiflu are already airing in epidemic proportions—not surprising considering that Roche has earned more than $18 billion off the drug since its introduction in 1999. As one financial analyst put it, Tamiflu is “a nice little earner.” I’ll say. But does it work? Continue reading
In my last 2 posts I talked about screening for colon cancer and breast cancer, respectively. Now it’s time to give men their due and discuss prostate cancer screening, specifically the use of PSA (prostate specific antigen) testing. Continue reading
In my last post about screening colonoscopies, I noted that the test harms 7 to 8 people for every one that benefits, but the harms are likely justified given that colonoscopy also has the capacity to prevent future cancers through polyp removal. I’m afraid the numbers for screening mammography in asymptomatic women to look for breast cancer are far worse. Here, it’s hard to make a case for universal screening. Continue reading
Medical screening tests harm more people than they help. It’s true, and like the sinking of the Titanic: “It’s a mathematical certainty.” Remember first that the goal of medical screening is to detect or prevent potentially fatal diseases in an asymptomatic population. And the reason most people in the population are asymptomatic is because they don’t have the disease in the first place. You have to screen many to benefit a few. Continue reading
Although there remains much to be skeptical about in the world of medicine, there is also the occasional study that promises optimism. So every now and again I will mix things up and talk about a drug, a device, or a treatment where there is strong evidence of value. Continue reading
It’s a slick procedure, all right; a bit of spinal anesthesia, just 3 tiny incisions, some sophisticated gadgetry, a bit of maneuvering and sloshing, and all done. Zip, zip, zip. The recovery times are short, the complications few, and the whole idea of operating on the knee without any major incisions is just so downright appealing that it’s no wonder arthroscopic surgery is the most common orthopedic surgery performed in America, done almost a million times a year to the tune of more than $5 billion. But does it work?